Intracellular transport and cell surface delivery of the neural cell adhesion molecule (NCAM)
نویسندگان
چکیده
منابع مشابه
Neural cell adhesion molecule (NCAM) and myoblast fusion.
Considerable evidence points to an involvement of neural cell adhesion molecule (NCAM) in myoblast fusion. Changes in the level of NCAM expression, isoform specificity, and localization in muscle cells and tissues correspond to key morphogenetic events during muscle differentiation and repair. Furthermore, anti-NCAM antibodies have been shown by others to reduce the rate of myoblast fusion, whe...
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A comparative study on the expression of the neural cell adhesion molecule (NCAM) in human neuroblastoma cell lines and tissues was undertaken. NCAMs are a family of closely related cell surface glycoproteins involved in cell-cell interactions. Using antibodies that recognise distinct epitopes on NCAM, their presence was shown in neuroblastoma, but these studies do not yield any information on ...
متن کاملRapid axonal transport of the neural cell adhesion molecule.
The neural cell adhesion molecule (NCAM) is a cell-surface glycoprotein that mediates cell-cell interactions in the nervous system during development. In the present study, we demonstrate that NCAM is axonally transported in 3-d-old chick retinal ganglion cells and that it travels within the fast component of axonal transport (FC). Proteins were radiolabeled in retinal ganglion cell bodies afte...
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The neural cell adhesion molecule (NCAM) may be as important in the heart as it is in the nervous system. NCAM is a cell surface glycoprotein which manifests great diversity in polypeptide isoform and glycosylation throughout cardiogenesis as well as neurogenesis. It is expressed on cardiac myocytes in the myocardium and on epicardial and endocardial cells as well as on the components that inne...
متن کاملChanges in neural cell adhesion molecule (NCAM) structure during vertebrate neural development.
Changes in carbohydrate and polypeptide form of the neural cell adhesion molecule (NCAM) have been documented during the development of central nervous system tissue in both chicken and frog. The carbohydrate variations reflect a high and low content of polysialic acid, and for the two vertebrates examined the expression of these forms is similar. At very early stages of neural development NCAM...
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ژورنال
عنوان ژورنال: BioArchitecture
سال: 2015
ISSN: 1949-0992,1949-100X
DOI: 10.1080/19490992.2015.1118194